Document Type : Case Report
Authors
1
Department of oral medicine & Radiology, Post Graduate Student, Maitri College Of Dentistry & Research Centre, Anjora, Durg, CG, 491001
2
Department of Oral & Maxillofacial Surgery, Professor, Maitri College of Dentistry & Research Centre, Anjora, Durg. CG, 491001
3
Department of Oral Medicine & Radiology, Professor, Maitri College of Dentistry & Research Centre, Anjora, Durg, CG, 491001
Abstract
Proliferative verrucous leukoplakia is a multifocal & progressive lesions of the oral mucosa, with unknown etiology & commonly resistant to all therapy attempts with frequent recurrence. It develops initially as a white plaque of hyperkeratosis that eventually becomes a multifocal disease with confluent, Exophytic & proliferative features.WHO 2005 described PVL as a rare but distinctive high risk clinical form of oral precursor lesions. Several studies have examined PVL characteristics and it’s propensity to develop into oral carcinoma. It is characterized by a high rate of oral squamous cell carcinoma & verrucous carcinoma transformation (higher than 70%). In our case report a diagnosed case of PVL was surgically excised with safe margin & reconstructed by buccal pad fat and PRF. Platelet-rich fibrins are a concentrated suspension of growth factors found in platelets, which act as bioactive surgical additives that are applied locally to induce healing.A normal PRF membrane has rapid degradability (1-2 weeks), but if fibres are cross-linked, it could provide resistance against enzymatic degradation and could be more stable during the healing time
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