The Role of OralID Guided Biopsy in Diagnosis of Oral Epithelial Dysplastic Lesions

Document Type : Original Article

Authors

Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Tanta University, Gharbia, Egypt

Abstract

Statement of the problem: Many lights based noninvasive diagnostic techniques has been developed that aids in the early
detection of oral cancer. Among these, autofluorescence based diagnostic techniques.
Purpose: This study designed to evaluate the diagnostic accuracy of OralID device in early diagnosis and guiding the margins
of biopsy in management of suspected oral dysplastic lesions.
Materials and Methods: Randomized clinical study was carried out on twenty selected patients with suspected oral mucosal
lesions were collected from the outpatient clinic of Oral and Maxillofacial Surgery Department, Faculty of Dentistry, Tanta
University. Areas clinically suspicious detected by conventional oral examination (COE) or direct visual fluorescence evaluation
(DVFE) were further investigated using surgical biopsy.
Results: The device showed sensitivity 100% and specificity 40%.
Conclusion: The study demonstrated its usefulness for clinical examination, monitoring oral lesions but the false negative test
result may limit its utility in taking a biopsy with a safety margin.

Keywords