Background: Most of the body’s tissues can undergo wound repair following a disruption of tissue integrity. Upon healing, these wounds result in scar formation. Botulinum Toxin A (BTA) is known to prevent fibroblast proliferation and it also induces temporary muscle paralysis. Also, mesotherapy is the non-invasive transdermal injection which can aid the skin to increase collagen and elastin production. Thus, both techniques are eligible for enhancement of facial scars.
Aim of this study: The study was proposed to compare between the efficacy of early postoperative Botulinum Toxin type A (BTA) injection and mesotherapy growth factor AQ recovery serum on the scar appearance.
Materials and methods: Thirty-three patients requiring treatment of facial scars by primary closure were selected for this study and were randomly distributed into three groups. Group A(n=11) received BTA injection while group B (n=11): received mesotherapy growth factor serum with a derma pen injection. Both groups received the injections within a period of 5 days after primary closure. Group C (n=11) the control group where no further treatment was given after primary closure. Follow-up of the patients was at 1, 3 and 6 months postoperatively to evaluate the wound scar enhancement using Vancouver scar scale (VSS) Scores and wound width, in addition to clinical photographs.
Results: Results were statistically analyzed and compared using the IBM Statistical Package for Social Science (SPSS) software version 22.0.
Conclusion: It can be concluded from this research that both BTA injection and mesotherapy using the micro-needling technique, offered exquisite outcomes on facial scars
Dessoky, N., & Noureldin, M. (2024). Botulinum toxin versus mesotherapy on enhancement of facial scarring (A Controlled Randomized Clinical Trial). Egyptian Journal of Oral and Maxillofacial Surgery, 15(4), 163-174. doi: 10.21608/omx.2024.317336.1262
MLA
Noha Youssry Dessoky; Marwa Gamal Noureldin. "Botulinum toxin versus mesotherapy on enhancement of facial scarring (A Controlled Randomized Clinical Trial)". Egyptian Journal of Oral and Maxillofacial Surgery, 15, 4, 2024, 163-174. doi: 10.21608/omx.2024.317336.1262
HARVARD
Dessoky, N., Noureldin, M. (2024). 'Botulinum toxin versus mesotherapy on enhancement of facial scarring (A Controlled Randomized Clinical Trial)', Egyptian Journal of Oral and Maxillofacial Surgery, 15(4), pp. 163-174. doi: 10.21608/omx.2024.317336.1262
VANCOUVER
Dessoky, N., Noureldin, M. Botulinum toxin versus mesotherapy on enhancement of facial scarring (A Controlled Randomized Clinical Trial). Egyptian Journal of Oral and Maxillofacial Surgery, 2024; 15(4): 163-174. doi: 10.21608/omx.2024.317336.1262
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