Report on an atypical case of non-Hodgkin's lymphoma type B of the subcutaneous soft tissues of the cheek region

Document Type : Case Report

Authors

Department of Reconstructive and Maxillofacial Surgery, Hassan II University Hospital of Fez, Sidi Mohamed Ben Abdellah University, Faculty of Medicine, Pharmacy, and Dentistry, Fez, Morocco.

Abstract

Primary extranodal non-Hodgkin's lymphoma (NHL) of the skeletal muscles is a well-recognized entity, although such occurrences are not very frequent. Even rarer is its presentation in the facial muscles.
This report details a case of a primitive extranodal type B non-Hodgkin's lymphoma in a non immunosuppressed patient involving only subcutaneous tissues and muscles of the cheek region and not extending to the oral cavity or sino-nasal passages. The patient was subsequently treated with chemotherapy and, at the time of writing, was in remission.
This case highlights the diagnostic challenges posed by atypical symptoms. Given the unusual presentation, it emphasizes the need to consider lymphoma as a potential cause of malignant infiltration in facial muscles. The rarity of such cases often leads to delays in diagnosis and treatment, underscoring the importance of awareness among clinicians. The patient's treatment response underscores the efficacy of chemotherapy in managing this rare manifestation of NHL.

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